发明名称 |
Use of IL-20 antagonists for alleviating spinal cord injury |
摘要 |
Alleviating neural injury, such as spinal cord injury, in a subject (e.g., a human subject) in need of the treatment using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway. |
申请公布号 |
US9512218(B2) |
申请公布日期 |
2016.12.06 |
申请号 |
US201414306693 |
申请日期 |
2014.06.17 |
申请人 |
National Cheng Kung University |
发明人 |
Chang Ming-Shi;Jou I-Ming |
分类号 |
A61K39/395;C07K16/24;A61K39/00 |
主分类号 |
A61K39/395 |
代理机构 |
Wolf, Greenfield & Sacks, P.C. |
代理人 |
Wolf, Greenfield & Sacks, P.C. |
主权项 |
1. A method for alleviating a neural injury in a subject, comprising administering to a subject in need thereof an effective amount of an IL-20 antagonist, wherein the neural injury is spinal cord injury (SCI), and wherein the IL-20 antagonist is an antibody that binds IL-20 or an antibody that binds an IL-20 receptor. |
地址 |
Tainan TW |