发明名称 2,3-DIHYDROIMIDAZOL[1,2-C]PYRIMIDIN-5(1H)-ONE BASED LIPOPROTEIN- ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2) INHIBITORS 23-[12-C]-5(1H)- A2(LP- PLA2)
摘要 The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
申请公布号 HK1216425(A1) 申请公布日期 2016.11.11
申请号 HK20160104389 申请日期 2016.04.18
申请人 GlaxoSmithKline Intellectual Property Development 发明人 SANG, Yingxia;WAN, Zehong;ZHANG, Qing
分类号 C07D;A61K;A61P 主分类号 C07D
代理机构 代理人
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