| 发明名称 | Method and composition of glycosaminoglycans in sickle cell and vascular disorders | ||
| 摘要 | A composition that includes a nanoparticle. The nanoparticle includes a shell which encapsulates sulfated non-anticoagulant heparin (SNACH). The shell includes poly L-arginine. The SNACH is ionically or covalently bonded to the poly L-arginine. A method for treating a disorder of a subject includes: administering to the subject a therapeutically effective amount of the composition for treating the disorder. The disorder is a vascular disorder, a complication of the vascular disorder, or a combination thereof. | ||
| 申请公布号 | US9480703(B2) | 申请公布日期 | 2016.11.01 |
| 申请号 | US201414526950 | 申请日期 | 2014.10.29 |
| 申请人 | Mousa Shaker A. | 发明人 | Mousa Shaker A. |
| 分类号 | A61K9/50;A61K9/14;A61K9/16;A61K31/727;A61K31/737;A61K9/51;A61K47/48;A61K31/00 | 主分类号 | A61K9/50 |
| 代理机构 | Schmeiser, Olsen & Watts, LLP | 代理人 | Schmeiser, Olsen & Watts, LLP ;Friedman Jack P. |
| 主权项 | 1. A composition, comprising: a nanoparticle comprising a shell which encapsulates sulfated non-anticoagulant heparin (SNACH), wherein the shell comprises poly L-arginine, and wherein the SNACH is ionically or covalently bonded to the poly L-arginine. | ||
| 地址 | Wynantskill NY US | ||