| 摘要 |
Title compds. (I; A = Ph, pyrid-2-yl, guinol-2yl, 1,8-naphthylidinyl; R = C1-4 alkanoyl), useful as tranquillizers, were prepd. by the reaction of II(R1 = H, C1-3 alkyl) and III. Thus, 0.90 cc butanoic acid was added in anhydrous methylene chloride suspension of 3.0 g 7-(7-chloro-1,8-naphthylidin-2-yl)-8-oxo-6-(pipeazin-1-yl)carbonyloxy-3,4,7,8-tetrahydro-2H, 6H-dithiepino[1,4 [2,3-C pyrrole and 2.0 g dicyclohexylcarbodiimide, and stirred at 20oC for 2 hr to give 2.6 g 6-(4-butyrylpiperazin-1-yl)-carbonyloxy-7(7-chloro-1,8-naphthylidin-2-yl)-8-oxo-2,4,7,8-tetrahydro-2H,6H-dithiepino[1,4 [2,3-C pyrrole.
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