发明名称 |
Embolic devices |
摘要 |
Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations of the vasculature with radiopaque hydrogel filaments with delayed controlled rates of expansion. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed. |
申请公布号 |
US9456823(B2) |
申请公布日期 |
2016.10.04 |
申请号 |
US201213450287 |
申请日期 |
2012.04.18 |
申请人 |
Terumo Corporation |
发明人 |
Constant Michael;Garretson Josh;Cruise Gregory M. |
分类号 |
A61B17/12;A61L31/06;A61L31/14;A61L31/18;A61M25/00;A61M25/01 |
主分类号 |
A61B17/12 |
代理机构 |
K&L Gates LLP |
代理人 |
K&L Gates LLP ;Cullman Louis C.;Novak Brian J. |
主权项 |
1. An expansile device for implantation comprising:
a polymeric filament including about 25% w/w poly (ethylene glycol) 10,000 macromer; about 11% w/w of an ethylenically unsaturated monomer; and about 63% w/w barium sulfate; an introducer configured to be connected to a catheter; a first pressurized liquid configured to flush the polymeric filament out of the introducer and into the catheter, wherein the first pressurized liquid has a pressure of between about 50 psi and about 200 psi; and a second pressurized liquid configured to flush the polymeric filament out of the catheter, wherein the second pressurized liquid has a pressure of between about 60 psi and about 140 psi, wherein the expansile device includes no metal support members. |
地址 |
JP |