Tissue repair implant

摘要

Described herein are tissue repair implants comprising at least a first layer of peritoneal membrane. The first layer of peritoneal membrane can be located adjacent to a second layer of peritoneal membrane and can be in direct contact with the second layer of peritoneal membrane. Additional layers (e.g., a third or fourth layer) can be included. Where more than one layer is present, the layers can be affixed to one another. For example, a first layer of peritoneal membrane can be attached to the second layer of peritoneal membrane by an adhesive bond, suture, or staple. One or more of the peritoneal membranes can be non-crosslinked, partially crosslinked, or substantially fully crosslinked. Any of the layers of peritoneal membrane may be attached to a wall (e.g., an interior or exterior wall) of an abdominal tissue by an adhesive, suture, and/or staples.

主权项

1. A tissue repair implant comprising a first layer of porcine peritoneal membrane comprising a first mesothelium surface and a second layer of porcine peritoneal membrane comprising a second mesothelium surface, wherein the first and second layers of porcine peritoneal membrane are derived from a sow, wherein the first and second layers of peritoneal membrane are attached with interrupted sutures, and wherein the first layer of porcine peritoneal membrane and the second layer of porcine peritoneal membrane are oriented with the first and second mesothelium surfaces in an outward direction to generate one or more adhesion-resistant organ contacting surfaces.