TREATMENT OF SKELETAL VOIDS WITH IMPLANTABLE SUBSTRATE HYDRATED WITH BONE MARROW CONCENTRATE

摘要

The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component and/or a 3D-printed implantable device. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

主权项

1. A 3D-printed implantable device, the device comprising:
an outer body that forms a periphery of the device, the outer body comprising:
a first angled bore oriented to direct a first screw passing therethrough towards an upper surface of the device; anda second angled bore oriented to direct a second screw passing therethrough towards a lower surface of the device; and a mesh disposed within the outer body.