BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF

摘要

There are disclosed a compound having the following formula: in which R<1> denotes a substituted or unsubstituted thiazolyl radical, a substituted or unsubstituted thiazolylmercapto radical or a substituted or unsubstituted phenyl radical; R<2> denotes a halogen atom, a cyano radical, a carbamoyl radical, a lower-alkylmercapto radical or an O-lower-alkylcarboxyimidoyl radical; and Y represents a group (wherein R<3> denotes hydrogen, a salt forming cation or a protective group for a carboxylic acid, and R<4> denotes hydrogen or a residue of a nucleophilic compound); process for preparing the same; and an intermediate compound useful for preparing the same. The above mentioned compound has a broad antibacterial spectrum and shows strong antibacterial activities against not only gram-positive bacteria but also gram-negative bacteria, particularly the resistive gram-negative becteria.