发明名称 |
Prosthetic devices coated with polypeptides with type IV collagen activity |
摘要 |
A composition which can bind heparin and promote cellular adhesion is provided which consists essentially of a polypeptide of the formula: met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg, thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr met, asn-pro-leu-cys-pro-pro-gly-thr-lys-ile-leu, or mixtures thereof, Medical devices such as prosthetic implants, percutaneous devices, bandages and cell culture substrates coated with the polypeptide composition are also provided.
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申请公布号 |
US5007925(A) |
申请公布日期 |
1991.04.16 |
申请号 |
US19890397012 |
申请日期 |
1989.08.22 |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
TSILIBARY, EFFIE C.;FURCHT, LEO T. |
分类号 |
G02C7/04;A61F2/02;A61K38/00;A61L15/16;A61L15/32;A61L27/00;A61L31/00;C07K7/06;C07K7/08;C07K14/78;C12M3/00;C12M3/04;C12N5/00;C12N5/06 |
主分类号 |
G02C7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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