发明名称 2'-DESOXY-ISOGUANOSIN, DESSEN ISOSTERE ANALOGE SOWIE ANWENDUNG DERSELBEN
摘要 2'-desoxy-isoguanosine, isoster analogues and isoguanosine derivates having the formulas (I) to (V) are disclosed, as well as a process for preparing the same from compounds having the general formulas (a) or (b) reacted with aroylisocyanates or from compounds having the general formulas (VI) to (IX) by photochemical irradiation. According to another process for preparing the same, desoxyguanosines or guanosines are persilylated, reacted with ammonia and desaminated in 2-position. These compounds are suitable as medicaments having an anti-viral activity.
申请公布号 DE4140463(A1) 申请公布日期 1993.06.17
申请号 DE19914140463 申请日期 1991.12.09
申请人 BOEHRINGER MANNHEIM GMBH, 6800 MANNHEIM, DE 发明人 SEELA, FRANK, PROF. DR.-CHEM., 4500 OSNABRUECK, DE;KASIMIRCZUK, ZYGMUNT, DR.-CHEM., WARSZAWA, PL;MUEHLEGGER, KLAUS, 8121 POLLING, DE;ELTZ, HERBERT VON DER, CIPL.-CHEM. DR., 8120 WEILHEIM, DE
分类号 C12P19/34;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7056;A61K31/7076;A61P31/12;C07H19/04;C07H19/052;C07H19/16;C07H19/20;C07H19/23;C07H21/00;C07H21/02;C07H21/04;C12Q1/68 主分类号 C12P19/34
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