ANTITUSSIVE

摘要

An antitussive containing a compound represented by general formula (I) or a salt thereof as the active ingredient, wherein symbol .^_.^_.^_ represents a double or single bond; R1 represents alkyl, cycloalkylalkyl, cycloalkenylalkyl, aryl, aralkyl, alkenyl, allyl, furan-2-ylalkyl or thiophene-2-ylalkyl; R2 represents hydrogen, hydroxy, nitro, alkanoyloxy, alkoxy, alkyl or -NR9R10, wherein R?9 and R10¿ represent each hydrogen, etc.; R3 represents hydrogen, hydroxy, alkanoyloxy or alkoxy; A represents -XC(=Y)-, -XC(=Y)Z-, -X-, -XSO¿2?- or -OC(OR?4)R4¿-, wherein X, Y and Z represent each independently NR4 (wherein R4 represents hydrogen, etc.), S or O; B represents a valence bond, alkylene, etc., acyclic unsaturated hydrocarbon, etc.; R5 represents hydrogen, benzene ring, etc.; R?6 and R7¿ represent each hydrogen, etc., or are combined together to represent -O-, -CH¿2?-, -S-, etc.; and R?8¿ represents hydrogen, alkyl or alkanoyl.