发明名称 |
Inhibitorer av rotamasenzymaktivitet |
摘要 |
This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration. |
申请公布号 |
SE9604097(L) |
申请公布日期 |
1996.12.08 |
申请号 |
SE19960004097 |
申请日期 |
1996.11.08 |
申请人 |
GUILFORD PHARM INC;UNIV JOHNS HOPKINS MED |
发明人 |
STEINER JOSEPH P;SNYDER SOLOMON;HAMILTON GREGORY S |
分类号 |
C07D491/04;A61K31/435;A61K31/4353;A61K31/436;A61K31/444;A61K31/445;A61K31/453;A61K31/4535;A61K31/4545;A61K31/495;A61K31/50;A61K31/5025;A61K31/70;A61K38/00;A61K38/18;A61K45/06;A61P25/00;A61P25/02;A61P25/28;A61P43/00;C07D211/60;(IPC1-7):A61K31/445 |
主分类号 |
C07D491/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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