PROCESS FOR PRODUCING TAXOL BY CELL CULTURE OF TAXUS

摘要

The invention provides a process for producing taxol, a anticancer drug, by tissue culture of yew. the process comprises the steps of: serial culture callus from yew tissue in media containing sodium phosphate and KCl; adding 1-20% by weight coconut water in the middle stage of culture to promote cell growth; adding at least a kind of heavy metal in the late stage of culture to improve amount of taxol. Copper sulfate, ferrous sulfate, cadmium sulfate and lead acetate can be used as heavy metals.