| 发明名称 |
SYNTHETIC METHYLOTROPHY TO LIQUID FUELS AND CHEMICALS |
| 摘要 |
A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided. |
| 申请公布号 |
US2016333308(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201515112364 |
申请日期 |
2015.01.09 |
| 申请人 |
Papoutsakis Eleftherios T.;Nicolaou Sergios;Fast Alan;Falara Vasiliki;Bennett Robert Kyle;Whitaker William Brian;Sandoval Nicholas Richard;Gonzalez Jacqueline;Antoniewicz Maciek |
发明人 |
Papoutsakis Eleftherios T.;Nicolaou Sergios;Fast Alan;Falara Vasiliki;Bennett Robert Kyle;Whitaker William Brian;Sandoval Nicholas Richard;Gonzalez Jacqueline;Antoniewicz Maciek |
| 分类号 |
C12N1/32;C12N15/52;C12N15/70;C12P7/16;C12N9/04 |
主分类号 |
C12N1/32 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A non-naturally occurring microbe capable of growing in a medium comprising methanol, wherein the methanol contributes to at least 40% of the carbon source for the non-naturally occurring microbe, expressing heterologous methanol dehydrogenase (MDH) and one or more heterologous ribulose monophosophate (RuMP) pathway enzymes. |
| 地址 |
Newark DE US |
