发明名称 SUBSTITUTED QUINAZOLINE DERIVATIVES.
摘要 This invention provides a compound having the formula (see formula) wherein X is phenyl which is optionally substituted; R and R1 are each, independently, hydrogen, halogen, alkyl, alkoxy, hydroxy, or trifluoromethyl; R2 is hydrogen, alkyl, alkoxy, hydroxy, trifluoromethyl; Y is a radical selected from the group consisting of (see formula) R3 is independently hydrogen, alkyl, carboxy, carboalkoxy, phenyl, or carboalkyl; n=2-4; or a pharmaceutically acceptable salt thereof, with the proviso that each R3 of Y may be the same or different which are useful as antineoplastic agents.
申请公布号 MX9700883(A) 申请公布日期 1997.08.30
申请号 MX19970000883 申请日期 1997.02.04
申请人 AMERICAN CYANAMID COMPANY 发明人 ALLAN WISSNER;BERNARD JEAN JOHNSON;MEDDLETON BRAWNER FLOYD;DOUGLAS BRUCE KITCHEN
分类号 A61K31/505;A61K31/517;A61P35/00;A61P43/00;C07D239/94;(IPC1-7):C07D239/94 主分类号 A61K31/505
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