| 摘要 |
The present invention describes indanylidineacetylguanidines I and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, r5, R6, r7, R8, R9, R10 and X have the meanings given in claims, are effective inhibitors of sodium/proton (Na+/H+ interchanger) cell anti-portage, which in various illness (essential hypertension, arteriosclerosis, diabetes and the like) is also increased in those cells which are easily accessible for measurements, such as, for example, erythrocytes, blood platelet or leukocytes. They are also advantageous for the preparation of a medicament for lipids metabolism disorder prophylaxis. |
