QUINOLINE AND ACRIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS

摘要

Compounds having formula (I) or (II) where R is primary or secondary amine or a group -L-Z, Y is H, halogen, alkyl, alkoxy, perfluoroalkyl, nitro or -L-Z, n is 1 to 4, L is a linker chain of 1-20 C, N, O or S atoms, and Z is a calcium channel blocker; have potassium channel blocking activity and are useful for the prophylaxis or therapy of arrhythmia.