| 摘要 |
<p>The invention concerns a peptide for the therapeutic or prophylactic treatment of hepatitis C, capable of reacting with a hepatitis C virus structure antigen specific antibody, comprising an amino acid sequence which imitates a conformational epitope of an antigen structure of said virus without, however, corresponding to a continuous amino acid sequence of said antigen, characterised in that said peptide comprises in particular assorted sequences 1 to 7. The invention also concerns a recombinant vector comprising a functional expression cassette for expressing a polynucleotide coding for said peptide. The invention further concerns a or composition for treating or preventing hepatitis C, in particular to be used as vaccine, whereof the active principle comprises said peptide, if required conjugate, and/or a recombinant vector coding for said peptide. The invention finally concerns the use of said peptide as reagent for diagnosing hepatitis C and/or susceptibility to chronicity in the event of hepatitis C infection.</p> |
