发明名称 |
A method for in vitro maturation of human gametes |
摘要 |
<heading lvl="0">Abstract of Disclosure</heading> The present invention relates to a method for in vitro maturation of a human gamete by culturing an immature human gamete in a chemically defined cell culture medium. The human gamete can be a spermatocyte or an oocyte. The maturation end point is metaII. The advantage of the described medium is a synchronised cumulus-, cytoand nuclear maturation completed within a period of 20 to 30 hours. The medium should preferably contain ATA (Aurin Tri Carboxylicacid) as an anti-apototic agent. The medium should preferably not contain BSA, HSA or other directly serum derived products or substances. |
申请公布号 |
AU4360599(A) |
申请公布日期 |
2000.01.10 |
申请号 |
AU19990043605 |
申请日期 |
1999.06.22 |
申请人 |
MEDI-CULT A/S |
发明人 |
SVEND LINDENBERG;ANNE LIS MIKKELSEN;STEVEN DALE SMITH;KJELL BERTHEUSSEN |
分类号 |
A61K38/00;C12N5/075;G01N33/68;G01N33/74 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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