发明名称 |
COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND SELECTIVE CYCLOOXYGENASE-2 INHIBITORS |
摘要 |
This invention is directed to methods, pharmaceutical compositions and kits comprising an aldose reductase inhibitor (ARI), a prodrug thereof or a pharmaceutically acceptable salt of said ARI or said prodrug and a selective COX-2 inhibitor,a prodrug thereof or a pharmaceutically acceptable salt of said selective COX-2 inhibitor or said prodrug. This invention further relates to methods of using those pharmaceutical compositions for the treatment of diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic retinopathy and diabetic cardiomyopathy.
|
申请公布号 |
CA2313063(A1) |
申请公布日期 |
2000.12.30 |
申请号 |
CA20002313063 |
申请日期 |
2000.06.29 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
MYLARI, BANAVARA LAKSHMAN |
分类号 |
A61K45/00;A61K31/18;A61K31/34;A61K31/341;A61K31/395;A61K31/404;A61K31/405;A61K31/41;A61K31/415;A61K31/4178;A61K31/4188;A61K31/42;A61K31/422;A61K31/425;A61K31/426;A61K31/427;A61K31/433;A61K31/44;A61K31/4439;A61K31/454;A61K31/47;A61K31/4725;A61K31/4747;A61K31/495;A61K31/50;A61K31/517;A61K31/5377;A61K45/06;A61P3/00;A61P3/10;A61P9/00;A61P13/12;A61P25/02;A61P27/02;A61P43/00;(IPC1-7):A61K31/404 |
主分类号 |
A61K45/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|