| 发明名称 |
CONTROL AND CHARACTERIZATION OF PSYCHOTIC STATES |
| 摘要 |
Provided herein are methods of inducing psychosis in animals using light-responsive opsins and methods of identifying or screening compounds that may be useful in treating psychosis. |
| 申请公布号 |
US2016316732(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201615214402 |
申请日期 |
2016.07.19 |
| 申请人 |
The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Deisseroth Karl;Sohal Vikaas;Gunaydin Lisa |
| 分类号 |
A01K67/027;C12N5/0793;A61K49/00;G01N33/50 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A non-human animal comprising a light-responsive opsin expressed on the cell membrane of a subset of layer V pyramidal neurons in the prefrontal cortex, wherein light activation of the opsin induces depolarization of the membrane and induces psychosis of the animal. |
| 地址 |
Stanford CA US |
