Benzoic acid derivatives and related compounds as antiarrhythmic agents

摘要

Benzoic acid derivatives of the formula I where X is oxygen, sulfur, -NH, -NR1, -N-CN, -N-OR1 or -N-NO2; Y is a single bond, -C=C-, or -NH; R1 is alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocyclo, or (heterocyclo)alkyl; and R2 is aryl or heterocyclo. The compounds of formula I are useful in the treatment of arrhythmia.