发明名称 |
SOLID DOSAGE FORMS OF DIVALPROEX SODIUM |
摘要 |
The present invention is directed to an aqueous process for granulating valproate compounds, in which the pH of the granulation solution is maintained at a pH of 5 or below. The invention is also directed to dosage forms in which the residual content of organic solvents is reduced to a level of 0.2w/w% or less. |
申请公布号 |
WO02051400(A3) |
申请公布日期 |
2002.12.27 |
申请号 |
WO2001US43158 |
申请日期 |
2001.11.27 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
QIU, YIHONG;ENGH, KEVIN, R.;FAITSCH, LYNN;SLADE, RUSSELL, T. |
分类号 |
A61K9/16;A61K9/20;A61K9/54;A61K31/19 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|