发明名称 SOLID DOSAGE FORMS OF DIVALPROEX SODIUM
摘要 The present invention is directed to an aqueous process for granulating valproate compounds, in which the pH of the granulation solution is maintained at a pH of 5 or below. The invention is also directed to dosage forms in which the residual content of organic solvents is reduced to a level of 0.2w/w% or less.
申请公布号 WO02051400(A3) 申请公布日期 2002.12.27
申请号 WO2001US43158 申请日期 2001.11.27
申请人 ABBOTT LABORATORIES 发明人 QIU, YIHONG;ENGH, KEVIN, R.;FAITSCH, LYNN;SLADE, RUSSELL, T.
分类号 A61K9/16;A61K9/20;A61K9/54;A61K31/19 主分类号 A61K9/16
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