摘要 |
<P>PROBLEM TO BE SOLVED: To obtain an application composition with fluidity, containing fine calcium phosphate particles for a bone prosthetic material with superior biological activity, and to provide a sheet type bone prosthetic material requiring not so long period of time for the growth of the bone. <P>SOLUTION: The bone prosthetic material composition for application having fluidity and the sheet type bone prosthetic material contain the fine calcium phosphate particles selected from the group consisting of dicalcium phosphate dihydrate CaHPO<SB>4</SB>-2H<SB>2</SB>O(DCPD), octacalcium phosphate Ca<SB>8</SB>H<SB>2</SB>(PO<SB>4</SB>)<SB>6</SB>-5H<SB>2</SB>O(OCP), whitlockite or tricalcium phosphate Ca(PO<SB>4</SB>)<SB>2</SB>(β-TCP, α-TCP), carbonate apatite, and calcium-OH-apatite Ca<SB>10</SB>(PO<SB>4</SB>)<SB>6</SB>(OH)<SB>2</SB>(HA), having the volume mean grain size of 3.5-8.0 μm, and substantially not containing coarse particles of the volume mean grain size of 9.0 μm or more. <P>COPYRIGHT: (C)2005,JPO&NCIPI |