| 摘要 |
1360001 Animal husbandry SCHERICO Ltd 16 June 1971 [16 March 1970] 4154/70 Heading A1M [Also in Divisions A5 and C2] Pregnant animals are treated with an androgenic active substituted anilide shortly before and/or during the period of Letal genital formation whereby litters produced consist solely of females and hermaphrodites, the said substituted anilide being of the general formula: or a pharmaceutically acceptable salt thereof wherein R represents a C 1-5 alkyl group of which carbon atoms at least one in secondary or tertiary; R' represents hydrogen or a C 1-6 alkyl group; B represents sulphur or oxygen; Y represents hydrogen, C 1-6 alkyl, halogen, nitro, carboxy (which may be esterified with a C 1-6 alkanol), hydroxy, C 1-6 alkoxy, C 1-6 alkanoyloxy, polyfluoro-C 1-6 alkoxy, polyfluoro-C 1-6 alkyl, trifluoromethylthio, trifluoromethylsulphoxy, trifluoromethylsulphonyl or C 1-6 alkanoyl; X represents iodine, trifluoromethyl, chlorine, bromine or iodine except a compound wherein B represents oxygen, R and R' are as defined above, and of X and Y, Y represents bromine, iodine, nitro, carboxy (which may be esterified with a C 1-6 alkanol), hydroxy, C 1-6 alkoxy, C 1-6 alkanoyl, C 1-6 alkanoyloxy, polyfluoro-C 1-6 alkoxy, trifluoromethylthio, trifluoromethylsulphoxy trifluoromethylsulphonyl or polyfluoro-C 1-6 -alkyl other than trifluoromethyl and X represents nitro, iodine, trifluoromethyl or bromine (X and Y not being both bromine); or Y represents trifluoromethyl and X represents iodine, bromine, or when R contains 6-8 carbon atoms of which at least two are secondary or tertiary ones, then X may also represent nitro. The substituted anilide may be administered in the form of a composition suitable for oral or parenteral administration and may be incorporated in an animal feedstock or feed-supplement. |
