发明名称 ACETYL SALICYCLIC ACID DIMERS, SYNTHESIS THEREOF, AND USES THEREOF TO PREVENT AND TREAT COMPLEMENT-MEDIATED DISORDERS
摘要 Dimers of acetyl salicylic acid, including 4,4′-diacetoxy-[1,1′-biphenyl]-3,3′-dicarboxylic acid (DAS-1) and 5,5′-methylenebis(2-acetoxybenzoic acid) (DAS-2) are provided. Methods of blocking the C3 convertase stage of the alternative complement pathway, preventing formation of the membrane attack complex of complement, and preventing or treating a complement-mediated disorder in a mammal including the step of administering dimers of acetyl salicylic acid are also provided.
申请公布号 US2016297743(A1) 申请公布日期 2016.10.13
申请号 US201415036212 申请日期 2014.11.17
申请人 AURIN BIOTECH INC. 发明人 MCGEER Patrick L.;LEE Moonhee;MCGEER Edith G.
分类号 C07C69/16;C07C69/017 主分类号 C07C69/16
代理机构 代理人
主权项
地址 Vancouver CA