发明名称 |
3-Formyl-7-amino-3-cephem-4-carboxylic acids prepn. - by oxidation of the 3-hydroxymethyl acid with hexavalent chromium in aqueous or N,N-dialkyl-alkanoic amide contg. medium |
摘要 |
<p>Process for the prepn. of opt. 7-substd.-3-formyl-7-amino-3-cephem-4-carboxylic acids (I) including their salts and lactonic hemiacetals by oxidn. of an opt. 7-substd. -3-hydroxymethyl-7-amino-3-cephem-4-carboxylic acid (II) salt with hexavalent-chromium in a medium contg. 2-25% (pref. 10-20%) water or oxidn. of the free acid (II) with hexavalent chromium in a medium contg. 2-25% (pref. 10-20%) N,N-di(lower alkyl)-lower alkanoic acid amide. Cpds. (I) are useful as antibacterials or inters.</p> |
申请公布号 |
DE2507355(A1) |
申请公布日期 |
1976.09.02 |
申请号 |
DE19752507355 |
申请日期 |
1975.02.20 |
申请人 |
SHIONOGI & CO.LTD. |
发明人 |
YOSHIOKA,MITSURU;SENDO,YUJI;MURAKAMI,MASAYUKI;MIYAZAKI,SADAO;ISHIKURA,KOJI |
分类号 |
C07D;C07D501/04;C07D501/26;(IPC1-7):C07D501/26 |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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