发明名称 PREPARATION OF THERAPEUTIC COMPOUNDS
摘要 A process is disclosed for preparing arylpropionic acids of formula Ar-CH(CH3)-COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar-C(OH)(CH3)-COOH or its amide, and converting the acid or amide to the product.
申请公布号 ZA7601825(B) 申请公布日期 1977.03.30
申请号 ZA19760001825 申请日期 1976.03.25
申请人 THE BOOTS CO LTD 发明人 NICHOLSON J;TURNER J
分类号 C07B31/00;C07B49/00;C07B61/00;C07C51/00;C07C51/36;C07C51/367;C07C51/377;C07C51/487;C07C57/30;C07C57/42;C07C57/46;C07C57/48;C07C57/52;C07C57/58;C07C57/60;C07C59/48;C07C59/56;C07C59/64;C07C59/68;C07C59/84;C07C59/90;C07C67/00;C07C301/00;C07C303/40;C07C311/21;C07D207/08;C07D207/32;C07D207/337;C07D211/34;C07D213/54;C07D213/55;C07D295/185;C07D307/54;C07D317/72;C07D333/24 主分类号 C07B31/00
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