摘要 |
<p>The present invention relates to the discovery that the administration of maltol or ethyl maltol at appropriate dosage levels and rates, significantly reduces the tobacco consumption of habitual smokers. In a preferred embodiment, finely divided ethyl maltol is distributed in a chewing gum base, which when chewed by the subject, results in a gradual release of ethyl maltol into the oral cavity. When administered in appropriate amounts over a period of several days, there results a gradual decrease in the number of cigarettes smoked and the length of time they are smoked. The reduction appears to be spontaneous and does not appear to be accompanied by the typical symptoms of nicotine withdrawal.</p> |