发明名称 |
DETECTING NEOPLASM |
摘要 |
This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided. |
申请公布号 |
US2016305946(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
US201615197105 |
申请日期 |
2016.06.29 |
申请人 |
Mayo Foundation for Medical Education and Research |
发明人 |
Taylor William R.;Harrington Jonathan J.;Quint Patrick S.;Zou Hongzhi;Bergen, III Harold S.;Smith David I.;Ahlquist David A. |
分类号 |
G01N33/574 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
1. A method of detecting pancreatic cancer in a mammal, wherein said method comprises determining the ratio of an elastase 3 A polypeptide to a pancreatic alpha-amylase polypeptide present within a stool sample, wherein the presence of a ratio greater than about 0.5 indicates that said mammal has said pancreatic cancer, and wherein the presence of a ratio less than about 0.5 indicates that said mammal does not have said pancreatic cancer. |
地址 |
Rochester MN US |