deA-steroids

摘要

The present disclosure is directed to 5-oxo- or methylene 17 beta -hydroxy saturated or unsaturated deA-steroids wherein the 17 alpha -position contains a propionic acid or propanol substituent and derivatives thereof wherein the hydroxy group at the 17-position forms a lactone ring with the carboxy substituent when the substituent at position 21 is carboxy. The deA-steroids and derivatives of the present disclosure are useful as potassium-sparing diuretics or for flushing oedemas.