发明名称 GUANIDINE COMPOUND
摘要 [Problem] The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a VAP-1 inhibitory activity, and as a result, they have found that the compound or a salt thereof of the present invention exhibits an excellent VAP-1 inhibitory activity and is useful for preventing and/or treating VAP-1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. In addition, the present invention relates to a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases, which comprises the compound or a salt thereof of the present invention, and an excipient.
申请公布号 HRP20160944(T1) 申请公布日期 2016.10.07
申请号 HR2016P000944T 申请日期 2016.07.25
申请人 Astellas Pharma Inc. 发明人 Yoshihara, Kousei;Suzuki, Daisuke;Yamaki, Susumu;Yamada, Hiroyoshi;Mihara, Hisashi;Seki, Norio
分类号 C07D205/04;A61K31/426;A61K31/4402;A61K31/4545;A61K31/495;A61K31/496;A61K31/505;A61K31/506;A61K31/5377;A61K31/551;A61P1/02;A61P1/04;A61P1/16;A61P3/04;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/00 主分类号 C07D205/04
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