发明名称 |
FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS |
摘要 |
Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated inimunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease. |
申请公布号 |
HUE027316(T2) |
申请公布日期 |
2016.10.28 |
申请号 |
HUE12715295 |
申请日期 |
2012.04.12 |
申请人 |
Newlink Genetics Corporation |
发明人 |
MAUTINO, Mario;KUMAR, Sanjeev;WALDO, Jesse;JAIPURI, Firoz;KESHARWANI, Tanay;ZHANG, Xiaoxia |
分类号 |
A61P37/02 |
主分类号 |
A61P37/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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