Multipart fluid system and a system for regional citrate anticoagulation in an extracorporeal blood circuit

摘要

A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mM total calcium and 2 to 8 mM citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mM citrate into the arterial blood line.

主权项

1. A multipart fluid system for treating extracorporeal blood comprising:
an extracorporeal blood passage including an inlet configured to receive blood withdrawn from a patient and an outlet configured to discharge treated blood to be infused into the patient; a pump configured to be coupled to the extracorporeal blood passage to simultaneously withdraw blood from the patient, pass withdrawn blood through the blood passage and infuse treated blood into the patient; a first fluid source configured to be in fluid communication with the extracorporeal blood passage, wherein the first fluid source contains an anticoagulation fluid including at least 8 mM citrate, and a second fluid source configured to be in fluid communication with the extracorporeal blood passage, wherein the second fluid source contains a blood treatment fluid comprising 2-8mM citrate and 1 to 5 mM total calcium.