发明名称 |
Contrast agent for NMR scanning |
摘要 |
Complexes formed between (a) an amino di- or poly-phosphonate in which phosphonate groups comprise separate carbon atoms and (b) a paramagnetic metal ion such as Gd3+, have calcified tissue seeking properties which make them useful as contrast agents for investigating bone metabolism by NMR scanning. Two preferred poly-phosphonates are ethylenediamine tetramethylphosphonate and meta-xylene-diamine tetramethylphosphonate.
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申请公布号 |
US4880007(A) |
申请公布日期 |
1989.11.14 |
申请号 |
US19860884622 |
申请日期 |
1986.07.11 |
申请人 |
AMERSHAM INTERNATIONAL PLC |
发明人 |
SADLER, PETER J.;HARDING, CHARLES T.;KELLY, JAMES D.;MCEWEN, ANDREW B. |
分类号 |
G01R33/28;A61B5/055;A61B10/00;A61K49/00;A61K49/06;C07F5/00;C07F9/38;C07F11/00;C07F13/00;C07F15/02;G01R33/32 |
主分类号 |
G01R33/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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