发明名称 Pharmaceutical composition and method containing gamma inulin or derivative thereof
摘要 PCT No. PCT/AU86/00311 Sec. 371 Date Aug. 3, 1987 Sec. 102(e) Date Aug. 3, 1987 PCT Filed Oct. 17, 1986 PCT Pub. No. WO87/02679 PCT Pub. Date May 7, 1987.A process for preparing gamma inulin comprising the steps of (a) recrystallizing crude inulin from water at a temperature below 37 DEG C. to obtain a suspension, (b) heating the suspension at a temperature of from about 25 DEG to 45 DEG C. for about 1-3 days, (c) further heating the suspension at a temperature of about 40 DEG to 55 DEG C. for about 0.5 to 1.5 hours, and (d) isolating insoluble gamma inulin from the suspension. A composition comprising particles of inulin or an inulin derivative in the gamma polymorphic form is characterized in that the particles have a low rate of solution in aqueous media above 30 DEG C., particularly above 37 DEG C. The composition is effective as the active component of an immunotherapeutic preparation for activation of the alternative pathway of complement, or for antitumor treatment.
申请公布号 US4954622(A) 申请公布日期 1990.09.04
申请号 US19870086634 申请日期 1987.08.03
申请人 THE AUSTRALIAN NATIONAL UNIVERSITY 发明人 COOPER, PETER D.
分类号 A61K31/715;A61P35/00;A61P37/00;C08B1/00;C08B37/00;C08B37/18 主分类号 A61K31/715
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