| 发明名称 |
POLYPEPTIDE-ANTIBODY CONJUGATE FOR INHIBITING CELL ADHESION |
| 摘要 |
A polypeptide-antibody conjugate is disclosed that contains an integrin-binding polypeptide operatively attached to an antibody molecule that immunoreacts with adhesitory cell surface antigens. Therapeutic compositions and methods using those compositions are also disclosed whereby the polypeptide-antibody conjugate can be used to inhibit cell adhesion and cell adhesion-dependent processes such as tumor growth and platelet aggregation.
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| 申请公布号 |
CA2016962(A1) |
申请公布日期 |
1990.11.17 |
| 申请号 |
CA19902016962 |
申请日期 |
1990.05.16 |
| 申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
CHERESH, DAVID A. |
| 分类号 |
A61K38/00;A61K47/48;C07K14/47;C07K16/28;C07K16/30;(IPC1-7):C07K19/00;C07K16/00;A61K39/44;C12N15/62 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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