发明名称 HLA-B27 TESTING
摘要 PCT No. PCT/AU87/00055 Sec. 371 Date Dec. 22, 1987 Sec. 102(e) Date Dec. 22, 1987 PCT Filed Feb. 26, 1987 PCT Pub. No. WO87/05398 PCT Pub. Date Sep. 11, 1987.A method for testing for the HLA-B27 antigen which comprises mixing with blood cells or blood cell lysates a first antibody capable of binding and blocking the HLA-B7 antigen and a second antibody capable of binding to the HLA-B27 antigen wherein said second antibody is labelled so as to be detectable and thereafter detecting for the said labelled second antibody. The second antibody is specific to the HLA-B27 antigen. It is found that the HLA-B7 antigen binds in significant quantities to the second antibody. Therefore it is necessary to block the HLA-B7 antigen with said first antibody.
申请公布号 US5059524(A) 申请公布日期 1991.10.22
申请号 US19870151515 申请日期 1987.12.22
申请人 THE UNIVERSITY OF MELBOURNE 发明人 MCKENZIE, IAN F. C.;TRAPANI, JOE
分类号 G01N33/569 主分类号 G01N33/569
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