发明名称 |
METHOD FOR PRODUCING TH-INDEPENDENT CYTOTOXIC T LYMPHOCYTES |
摘要 |
2092548 9205794 PCTABS00011 The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.
|
申请公布号 |
CA2092548(A1) |
申请公布日期 |
1992.03.29 |
申请号 |
CA19912092548 |
申请日期 |
1991.09.24 |
申请人 |
IMMUNEX CORPORATION;UNIVERSITY OF WASHINGTON |
发明人 |
GREENBERG, PHILIP D.;OVERELL, ROBERT W. |
分类号 |
A61K35/14;C07K14/715;C12N5/0783;C12N5/10;C12N15/09;C12N15/12;C12N15/24;C12P21/02;(IPC1-7):C12N5/10;C12N15/25;C12N15/86;A61K35/18 |
主分类号 |
A61K35/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|