发明名称 METHOD FOR PRODUCING TH-INDEPENDENT CYTOTOXIC T LYMPHOCYTES
摘要 2092548 9205794 PCTABS00011 The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.
申请公布号 CA2092548(A1) 申请公布日期 1992.03.29
申请号 CA19912092548 申请日期 1991.09.24
申请人 IMMUNEX CORPORATION;UNIVERSITY OF WASHINGTON 发明人 GREENBERG, PHILIP D.;OVERELL, ROBERT W.
分类号 A61K35/14;C07K14/715;C12N5/0783;C12N5/10;C12N15/09;C12N15/12;C12N15/24;C12P21/02;(IPC1-7):C12N5/10;C12N15/25;C12N15/86;A61K35/18 主分类号 A61K35/14
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