Host biomarkers for Dengue fever (DF) and methods thereof
摘要
The present invention provides methods of determining whether a subject has a Dengue virus infection that is likely to develop into a life-threatening Dengue disease and methods of selecting a treatment regimen for a subject in need thereof who has been infected with a Dengue virus. The invention further provides a prognostic kit for distinguishing a subject who is likely to develop a mild Dengue disease from a subject who is likely to develop a life -threatening Dengue disease. The methods and kits of the invention can be used to differentiate DHF from DF and severe and non-severe forms of Dengue with high sensitivity and specificity.
申请公布号
AU2013240189(B2)
申请公布日期
2016.10.13
申请号
AU20130240189
申请日期
2013.03.15
申请人
National University of Singapore;Duke University
发明人
Abraham, Soman Ninan;St. John, Ashley Lauren;Ng, Mary Mah Lee;Raghavan, Bhuvanakantham