发明名称 SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS
摘要 <p>A compound of formula (I), in which R1 is carboxy or protected carboxy, R2 is 1-hydroxyethyl, R3 is methyl, R4 is optionally substituted pyridyl(lower)alkyl, optionally N-substituted 2-oxopiperazin-1-yl-(lower)alkyl, optionally substituted imidazol-1-yl(C¿2?-C3)alkyl, optionally substituted imidazol-5-yl(lower)alkyl, optionally substituted imidazol-2-yl-(lower)alkyl, optionally substituted pyrazol-4-(or 5-)yl(lower)alkyl, optionally substituted pyrazol-1-ylethyl, optionally substituted triazolyl(lower)alkyl, optionally substituted pyrimidinyl(lower)-alkyl, optionally substituted dihydropyrimidinyl(lower)alkyl, or optionally substituted (2,3-dihydroimidazo-[1,2-b]pyrazol-1-yl)ethyl, and R?5¿ is hydrogen or imino-protective group, and pharmaceutically acceptable salts thereof, which have antimicrobial activity.</p>
申请公布号 WO1993021186(A1) 申请公布日期 1993.10.28
申请号 JP1993000469 申请日期 1993.04.09
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