发明名称 SOLID PHARMACEUTICAL DOSAGE FORMS HAVING AN EXTENDED TWO-STAGE RELEASE PROFILE AND PRODUCTION THEREOF
摘要 <p>The present invention provides solid pharmaceutical compositions in dosage form containing an active ingredient or principle, preferably memantine, which exhibit an extended two-phase release profile and which are characterized by the presence of both a water-soluble and a water-insoluble salt of casein, preferably sodium and calcium caseinate, in the matrix thereof, in broad proportions and in a total amount between 5 and 98 % by weight of the composition, and with a process for the production thereof.</p>
申请公布号 WO1994003158(A1) 申请公布日期 1994.02.17
申请号 EP1993002074 申请日期 1993.08.04
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