发明名称 |
Antimicrobial quinolone thioureas |
摘要 |
<p>Antimicrobial quinolone thiourea compounds of the general formula: <IMAGE> wherein (1) A1, A2, A3, R1, R3, R4, and R6 form any of a variety of quinolone and related heterocyclic structures similar to those known in the art to have antimicrobial activity; and (2) (1) R1 is X, R3 is X, or both R1 and R3 are X; and X is the thiourea containing moiety and pharmaceutically-acceptable salts and biohydrolyzable esters thereof, and hydrates thereof.</p> |
申请公布号 |
PH30053(A) |
申请公布日期 |
1996.11.08 |
申请号 |
PH19300000422 |
申请日期 |
1991.04.01 |
申请人 |
NORWICH EATON PHARMACEUTICALS, INC. |
发明人 |
DEMUTH, THOMAS PROSSER, JR.;WHITE RONALD EUGENE |
分类号 |
C07D499/897;A61K31/435;A61K31/47;A61K31/535;A61K31/545;A61K31/546;A61P31/04;A61P43/00;C07D215/56;C07D237/28;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D409/12;C07D417/12;C07D417/14;C07D455/04;C07D463/00;C07D471/04;C07D477/10;C07D487/04;C07D498/04;C07D498/06;C07D499/00;C07D499/04;C07D499/86;C07D499/87;C07D499/88;C07D501/00;C07D501/18;C07D501/20;C07D501/34;C07D503/00;C07D505/00;C07D513/04;C07D513/06;C07D513/16;C07D519/00;C07D519/06;C07D521/00;C07F9/6561 |
主分类号 |
C07D499/897 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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