发明名称 |
DNA encoding stationary phase, stress response sigma factor from Mycobacterium tuberculosis |
摘要 |
SigF is a gene that controls M. tuberculosis latency. A diagnostic test for latent tuberculosis involves detecting M. tuberculosis sigF in clinical specimens. A tuberculosis vaccine includes a M. tuberculosis strain with a mutation which disrupts the reading frame of its sigF gene.
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申请公布号 |
US5700925(A) |
申请公布日期 |
1997.12.23 |
申请号 |
US19960622353 |
申请日期 |
1996.03.27 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
BISHAI, WILLIAM R.;YOUNG, DOUGLAS B.;ZHANG, YING;DEMAIO, JAMES |
分类号 |
C07K14/35;C07K16/12;(IPC1-7):C07H21/02;C07H21/04;C12N9/00 |
主分类号 |
C07K14/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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