BENZAZEPINONE-N-ACETIC ACID DERIVATIVES HAVING A PHOSPHONIC ACID GROUP, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS

摘要

New phosphono-substituted benzazepinone derivatives are neutral endopeptidase and endothelin converting enzyme inhibitors 3-(1-Phosphonomethyl-cyclopentane-1-carbonylamino)-2,3,4,5- tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid derivatives (I) are new. Benzazepine derivatives of formula (I) and their salts are new: R1-R3 = H or biolabile ester residue. An Independent claim relates to the preparation of (I).