发明名称 |
Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists |
摘要 |
Compounds of the formula, and pharmaceutically-acceptable salts thereof, which are useful as antagonists of the pain-enhancing effects of E-type prostaglandins, processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for treating pain comprising the administration of such compounds.
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申请公布号 |
US6057345(A) |
申请公布日期 |
2000.05.02 |
申请号 |
US19980183578 |
申请日期 |
1998.10.30 |
申请人 |
ZENECA LIMITED |
发明人 |
BREAULT, GLORIA ANNE;OLDFIELD, JOHN;TUCKER, HOWARD;WARNER, PETER |
分类号 |
C07D233/64;A61K31/165;A61K31/19;A61K31/415;A61K31/44;A61K31/4402;A61K31/50;A61P25/04;A61P43/00;C07C51/09;C07C63/04;C07C63/331;C07C65/105;C07C65/21;C07C65/24;C07C227/18;C07C229/38;C07C229/52;C07C229/60;C07C233/65;C07C233/69;C07C237/30;C07C237/32;C07C323/60;C07C323/62;C07D213/38;C07D213/55;C07D213/75;C07D213/80;C07D213/82;C07D233/54;C07D237/24;(IPC1-7):C07C233/02;C07C233/11;C07C233/64;A61K31/166 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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地址 |
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