USE OF FURIN AND FURIN-LIKE PROTEASE INHIBITORS IN THE TREATMENT OF INFLAMMATORY OR MATRIX REMODELLING DISEASES

摘要

The present invention provides methods, uses and compositions of an .alpha.1-antitrypsin variant called PDX or a construct, variant, analog, peptide, peptidomimetic, salt, complex or derivative thereof for the treatment of inflammatory or erosive diseases such as rheumatoid arthritis.