发明名称 COMPOSITION FOR VECTORIZING AN ANTI-CANCER AGENT.
摘要 The invention relates to a stable water-in-oil emulsion composition containing: 20% to 40% (v/v) aqueous phase in the form of droplets and containing an anti-cancer agent; and 60% to 80% (v/v) lipid phase containing an iodized oil and at least one surfactant, having Formula (I), in a proportion, of surfactant mass relative to the total volume of the composition, of 0.3% to 5%, formula (I) for said surfactant being the following in which: s has a value of 0 or 1; m is a whole number from 2 to 30; R1 is a Formula (II) grouping wherein n is a whole number from 4 to 10, o is a whole number from 1 to 4, p is a whole number from 3 to 7; q is a whole number from 2 to 10, and r has a value of 0 or 1; R2 is a hydrogen atom or is identical to R1; and each R3 is, separately, a hydrogen atom or is identical to R1. The invention also relates to an emulsion obtained from said composition, to the preparing method thereof, and to the use thereof for treating cancer and the metastases thereof.
申请公布号 MX2016010217(A) 申请公布日期 2016.12.05
申请号 MX20160010217 申请日期 2015.02.06
申请人 GUERBET 发明人 Caroline ROBIC;Jean- François MAYER
分类号 A61K31/704;A61K9/107;A61K47/14;A61K47/44;A61K51/12 主分类号 A61K31/704
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