发明名称 PROCESS FOR THE PREPARATION OF BENZODIAZEPINES
摘要 <p>Cpds. of formula (I): (where R1 is H, halogen, lower alkyl or NO2 (pref. 7-Cl 7-NO2); R2 is H, lower alkyl or di(lower alkyl)amino-lower alkyl (pref. H, Me or 2-diethylaminoethyl); R3 is pyridyl phenyl or halophenyl (pref. Ph, 2-pyridyl or 2-fluoro- or 2-chlorophenyl); B is CO or CH2) prepd. by treating a cpd. (II); with a reducing agent, pref. HI (esp. formed in situ) or NH2OH. Cpds. (I) are sedatives, tranquillisers, anticonvulsants and muscle relaxants.</p>
申请公布号 CA967955(A) 申请公布日期 1975.05.20
申请号 CA19720138901 申请日期 1972.04.05
申请人 HOFFMANN-LA ROCHE LIMITED 发明人 NING, ROBERT Y.;STERNBACH, LEO H.
分类号 C07D243/26;C07D498/04 主分类号 C07D243/26
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