KOVALENT AN KUNSTSTOFFE GEBUNDENE BIOLOGISCHE SUBSTANZEN UND IHRE VERWENDUNG IN DER RADIOCHEMISCHEN ANALYSE

摘要

1498081 Reagent treated tubes for analysis SMITH KLINE INSTRUMENTS Inc 2 Oct 1975 [4 Oct 1974] 40342/75 Heading G1B [Also in Division C3] Plastic tubes, e.g. of polypropylene, for use in radioimmunoassay procedures are treated internally with glutaraldehyde to form a glutaraldehyde polymer coating on the inside surface to which is then bonded a protein which is an immunological counterpart of an antigen to be assayed. The tube may be first impregnated with an amine. After the immunological counterpart has been coupled, the material to be assayed e.g. thyroxine vitamin B 12 or folic acid is incubated in the tube together with a radio-actively labelled derivative and the product counted with a detection device and compared with a standard.